Endocrinology

LIST OF CLINICAL TRIALS BY THERAPEUTIC AREA

Drug: Pioglitazone

1. Indication: type 2 diabetes
2. Manufacturer: Takeda, with Abbott (Commercial Agreement in Latin America)
3. Study: Efficacy and safety of pioglitazone for the treatment of metabolic syndrome patients.
   • Role: protocol development, feasibility and site selection
   • Ph2 study
   • Status: CSR available

Drug: Levothyroxine

1. Indication: hypothyroidism
2. Manufacturer: Abbott
3. Study: Low prevalence of hypothyroidism among black and Mulatto people in a population-based study of Brazilian women. Clinical Endocrinology (2007) 66, 803–807
   • Role: protocol development, site selection, author
   • Epidemiology study, prevalence study
   • Status: published (attached)

Drug: Sibutramine

1. Indication: obesity
2. Manufacturer: Abbott
3. Study: Blood pressure changes associated with sibutramine and weight management – an analysis from the 6-week lead-in period of the sibutramine cardiovascular outcomes trial (SCOUT). Diabetes, Obesity and Metabolism, 11, 2009, 239–250
   • Role: feasibility, site selection, site management (n = 500 patients in Brazil)
   • Status: published (attached)